Fasting, the deliberate abstention from food or specific types of food for a defined period, has gained significant attention in both scientific and traditional wellness communities. Beyond cultural and religious practices, the science of fasting has garnered attention for its potential health benefits and the intriguing physiological changes it induces. This article delves into the science behind fasting, exploring its known benefits and providing insights from the ancient Ayurvedic tradition, offering holistic advice for those considering incorporating fasting into their lifestyles.