The brain doesn’t just respond to the gut, it can initiate rapid changes in gut microbial composition through its own neuroendocrine signaling. We are entering an era of real-time mind–microbiome modulation investigation. This study invites us to think beyond probiotics and dietary changes alone. It reminds us that the brain is not just a passive recipient of microbial signals—it’s a dynamic conductor in the symphony of gut ecology.
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